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2018-5-15 To measure and classify the structural similarity of miRNAs, we propose a new three-dimensional (3D) graphical representation of the secondary structure of miRNAs, in which an miRNA secondary structure is initially transformed into a characteristic sequence based on physicochemical properties and frequency of base. To measure and classify the structural similarity of miRNAs, we propose a new three-dimensional (3D) graphical representation of the secondary structure of miRNAs, in which an miRNA secondary structure is initially transformed into a characteristic sequence based on physicochemical properties and frequency of base.
The method of mechanics of materials is limited to very simple structural elements under relatively simple loading conditions. The structural elements and loading conditions allowed, however, are sufficient to solve many useful engineering problems. The theory of elasticity allows the solution of structural elements of general geometry under general loading conditions, in principle. Analytical solution, however, is limited to relatively simple cases. The solution of elasticity problems also requires the solution of a system of partial differential equations, which is considerably more mathematically demanding than the solution of mechanics of materials problems, which require at most the solution of an ordinary differential equation.
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In engineering, stress analysis is often a tool rather than a goal in itself; the ultimate goal being the design of structures and artifacts that can withstand a specified load, using the minimum amount of material or that satisfies some other optimality criterion. Stress analysis may be performed through classical mathematical techniques, analytic mathematical modelling or computational simulation, experimental testing, or a combination of methods. The term stress analysis is used throughout this article for the sake of brevity, but it should be understood that the strains, and deflections of structures are of equal importance and in fact, an analysis of a structure may begin with the calculation of deflections or strains and end with calculation of the stresses. Contents • • • • • • • • • • • • • • • • • • • Scope [ ] General principles [ ] Stress analysis is specifically concerned with solid objects. The study of stresses in liquids and gases is the subject of. Stress analysis adopts the macroscopic view of materials characteristic of, namely that all properties of materials are homogeneous at small enough scales. Thus, even the smallest considered in stress analysis still contains an enormous number of atoms, and its properties are averages of the properties of those atoms.
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